Oh yeah, I know that some games hate Crossfire and SLI, but at least I can turn off Crossfire if a game is having too many problems. I haven't really seen any texture glitches today with Overwatch and the instances I saw yesterday could be counted on one hand and they were fairly minor so it's just something to tolerate for a performance boost.That's due to the crossfire.
Some games really don't like it. SLI has similar problems, but you can tweak that somewhat to fix some issues.